Kusuri Masuizai Koi Sedate 250ml 
 
Kusuri's full sedation formulation is very safe to use. Koi Sedate (Masuizai) does not contain any harmful Acetone. 
 
Full easy to use instructions on every bottle. 
 
Starting dose 10 ml to 2 gallons of pond water in a suitable bowl. Then add extra as required as temperature plays a big role in fish sedation.
 
Having said that, Masuizai is safe to use at any temperature.